Ligand binding and allostery can emerge simultaneously
نویسندگان
چکیده
منابع مشابه
Ligand binding and allostery can emerge simultaneously.
A heterotropic allosteric effect involves an effector molecule that is distinct from the substrate or ligand of the protein. How heterotropic allostery originates is an unanswered question. We have previously created several heterotropic allosteric enzymes by recombining the genes for TEM1 beta-lactamase (BLA) and maltose binding protein (MBP) to create BLAs that are positively or negatively re...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2007
ISSN: 0961-8368,1469-896X
DOI: 10.1110/ps.062706007